According to Prof. Craig Dukes, "Cosmic rays can be a real pain."  Dukes contributed a Fermilab "News at work" article discussing the work that he and his collaborators are doing to mitigate the adverse effects of cosmic ray muons on their neutrino physics experiments.

The UVA group, which includes professor Craig Group, research scientists Ralf Ehrlich and Yuri Oksuzian, graduate student Steve Boi, and many undergraduate students, will be fabricating the Mu2e Cosmic Ray Veto in the High Energy Physics Laboratory, before shipping it out to Fermilab.  It will be the largest construction project ever done by the UVA High Energy Physics Group.

See the article at:
http://news.fnal.gov/2016/10/cosmic-rays-pain/